Systemic Lupus Erythematosus with targetoid lesions: “Rowell Syndrome” or a rare manifestation of Lupus Erythematosus
نویسندگان
چکیده
Rowell syndrome is usually diagnosed by the presence of erythema multiforme like targetoid lesions in the patients of cutaneous or systemic lupus erythematosus and characterized by specific serological or immunological profile like speckled antinuclear antibody pattern, antibody against saline extract of human tissues (anti-SjT) and positive serum rheumatoid factor.The absence of a universally accepted criteria and their poor specificity usually make the diagnosis very difficult and doubtful. Moreover in the light of histopathological revealation of dermal mucin deposition alongwith the interface changes and necrotic basal keratinocytes in the absence of serum positivity for ANA antibody and RF, true existence of this syndrome is still debated. Herein we report a case of SLE having targetoid lesions on palm and soles & histopathological findings of both lupus erythematosus and erythema multiforme.
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